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1

Voices of biotech

Amit, Ido, Baker, David, Barker, Roger, Berger, Bonnie, Bertozzi, Carolyn, Bhatia, Sangeeta, Biffi, Alessandra, Demichelis, Francesca, Doudna, Jennifer, Dowdy, Steven F, Endy, Drew, Helmstaedter, Mori

Journal:

Nature Biotechnology

Year:

2016

Language:

english

File:

PDF, 3.22 MB

english, 2016

2

Overcoming cellular barriers for RNA therapeutics

Dowdy, Steven F

Journal:

Nature Biotechnology

Year:

2017

Language:

english

File:

PDF, 1.31 MB

english, 2017

3

10.1038/47100

Dowdy, Steven F., Vocero-Akbani, Adita M., Heyden, Nancy Vander, Lissy, Natalie A., Ratner, Lee

Journal:

Year:

1999

Language:

english

File:

PDF, 126 KB

english, 1999

4

10.1038/47105

Dowdy, Steven F., Vocero-Akbani, Adita M., Heyden, Nancy Vander, Lissy, Natalie A., Ratner, Lee

Journal:

Year:

1999

Language:

english

File:

PDF, 120 KB

english, 1999

5

10.1038/47120

Dowdy, Steven F., Vocero-Akbani, Adita M., Heyden, Nancy Vander, Lissy, Natalie A., Ratner, Lee

Journal:

Year:

1999

Language:

english

File:

PDF, 159 KB

english, 1999

6

10.1038/47126

Dowdy, Steven F., Vocero-Akbani, Adita M., Heyden, Nancy Vander, Lissy, Natalie A., Ratner, Lee

Journal:

Year:

1999

Language:

english

File:

PDF, 207 KB

english, 1999

7

10.1038/47109

Dowdy, Steven F., Vocero-Akbani, Adita M., Heyden, Nancy Vander, Lissy, Natalie A., Ratner, Lee

Journal:

Year:

1999

Language:

english

File:

PDF, 116 KB

english, 1999

8

10.1038/47114

Dowdy, Steven F., Vocero-Akbani, Adita M., Heyden, Nancy Vander, Lissy, Natalie A., Ratner, Lee

Journal:

Year:

1999

Language:

english

File:

PDF, 214 KB

english, 1999

9

10.1038/47123

Dowdy, Steven F., Vocero-Akbani, Adita M., Heyden, Nancy Vander, Lissy, Natalie A., Ratner, Lee

Journal:

Year:

1999

Language:

english

File:

PDF, 148 KB

english, 1999

10

Efficient siRNA delivery into primary cells by a peptide transduction domain–dsRNA binding domain fusion protein

Eguchi, Akiko, Meade, Bryan R, Chang, Yung-Chi, Fredrickson, Craig T, Willert, Karl, Puri, Nitin, Dowdy, Steven F

Journal:

Nature Biotechnology

Year:

2009

Language:

english

File:

PDF, 438 KB

english, 2009

11

RNA Therapeutics (Almost) Comes of Age: Targeting, Delivery and Endosomal Escape

Dowdy, Steven F., Levy, Matthew

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2018

Language:

english

File:

PDF, 356 KB

english, 2018

12

Controlling CRISPR-Cas9 Gene Editing

Phimister, Elizabeth G., Dowdy, Steven F.

Journal:

New England Journal of Medicine

Year:

2019

Language:

english

File:

PDF, 437 KB

english, 2019

13

Two‐pore channels regulate Tat endolysosome escape and Tat‐mediated HIV‐1 LTR transactivation

Khan, Nabab, Halcrow, Peter W., Lakpa, Koffi L., Afghah, Zahra, Miller, Nicole M., Dowdy, Steven F., Geiger, Jonathan D., Chen, Xuesong

Journal:

The FASEB Journal

Year:

2020

Language:

english

File:

PDF, 1.34 MB

english, 2020

14

Reversing a model of Parkinsonâs disease with in situ converted nigral neurons

Qian, Hao, Kang, Xinjiang, Hu, Jing, Zhang, Dongyang, Liang, Zhengyu, Meng, Fan, Zhang, Xuan, Xue, Yuanchao, Maimon, Roy, Dowdy, Steven F., Devaraj, Neal K., Zhou, Zhuan, Mobley, William C., Cleveland

Journal:

Year:

2020

File:

PDF, 13.87 MB

2020

15

Irradiation microcell-mediated chromosome transfer (XMMCT): The generation of specific chromosomal arm deletions

Steven F. Dowdy, David J. Scanlon, Clare L. Fasching, Graham Casey, Dr. Eric J. Stanbridge

Journal:

Genes, Chromosomes and Cancer

Year:

1990

Language:

english

File:

PDF, 915 KB

english, 1990

16

Correlation of the inability to sustain growth in defined serum-free medium with the suppression of tumorigenicity in Wilms' nephroblastoma

Steven F. Dowdy, Bernard E. Weissman, Eric J. Stanbridge

Journal:

Journal of Cellular Physiology

Year:

1991

Language:

english

File:

PDF, 1006 KB

english, 1991

17

52 TAT mediated protein transduction into cells: Examination of the phosphorylation status of the retinoblastona protein in vivo

David Gius, Adita M. Vocero-Akbani, Michael Wei, Steven F. Dowdy

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1997

Language:

english

File:

PDF, 122 KB

english, 1997

18

Protein transduction technology

Jehangir S Wadia, Steven F Dowdy

Journal:

Current Opinion in Biotechnology

Year:

2002

Language:

english

File:

PDF, 59 KB

english, 2002

19

Safety guidance for laboratory personnel working with trans-activating transduction protein transduction domains

Bruce D Backus, Steven F Dowdy, Kenneth R Boschert, Tracy L Richards, Michelle Becker-Hapak

Journal:

Chemical Health and Safety

Year:

2001

Language:

english

File:

PDF, 1.13 MB

english, 2001

20

Neuromuscular dysfunction acquired in critical illness: a

Robert D. Stevens, David W. Dowdy, Robert K. Michaels, Pedro A. Mendez-Tellez, Peter J. Pronovost, Dale M. Needham

Journal:

Intensive Care Medicine

Year:

2007

Language:

english

File:

PDF, 433 KB

english, 2007

21

10.1038/35036608

Dowdy, Steven F., Lissy, Natalie A., Davis, Penny K., Irwin, Meredith, Kaelin, William G.

Journal:

Year:

2000

Language:

english

File:

PDF, 154 KB

english, 2000

22

Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration

Nagahara, Hikaru, Vocero-Akbani, Adamina M., Snyder, Eric L., Ho, Alan, Latham, Dawn G., Lissy, Natalie A., Becker-Hapak, Michelle, Ezhevsky, Sergei A., Dowdy, Steven F.

Journal:

Nature Medicine

Year:

1998

Language:

english

File:

PDF, 418 KB

english, 1998

23

10.1038/4710

Dowdy, Steven F., Vocero-Akbani, Adita M., Heyden, Nancy Vander, Lissy, Natalie A., Ratner, Lee

Journal:

Nature Medicine

Year:

1999

Language:

english

File:

PDF, 316 KB

english, 1999

24

Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis

Wadia, Jehangir S, Stan, Radu V, Dowdy, Steven F

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 2.02 MB

english, 2004

25

Cell Penetrating Peptides in Drug Delivery

Eric L. Snyder, Steven F. Dowdy

Journal:

Pharmaceutical Research

Year:

2004

Language:

english

File:

PDF, 67 KB

english, 2004

26

Expression, purification, and functional characterization of adenovirus 5 and 12 E1A proteins produced in insect cells

Daniel S. Peeper, Alt Zantema, Steven F. Dowdy, Alex J. van der Eb

Journal:

Year:

1992

Language:

english

File:

PDF, 3.65 MB

english, 1992

27

Transmembrane delivery of protein and peptide drugs by TAT-mediated transduction in the treatment of cancer

Jehangir S. Wadia, Steven F. Dowdy

Journal:

Advanced Drug Delivery Reviews

Year:

2005

Language:

english

File:

PDF, 209 KB

english, 2005

28

Exogenous siRNA delivery using peptide transduction domains/cell penetrating peptides

Bryan R. Meade, Steven F. Dowdy

Journal:

Advanced Drug Delivery Reviews

Year:

2007

Language:

english

File:

PDF, 175 KB

english, 2007

29

Enhancing the cellular uptake of siRNA duplexes following noncovalent packaging with protein transduction domain peptides

Bryan R. Meade, Steven F. Dowdy

Journal:

Advanced Drug Delivery Reviews

Year:

2008

Language:

english

File:

PDF, 168 KB

english, 2008

30

Protein transduction domain delivery of therapeutic macromolecules

Arjen van den Berg, Steven F Dowdy

Journal:

Current Opinion in Biotechnology

Year:

2011

Language:

english

File:

PDF, 412 KB

english, 2011

31

The kinetics and tissue distribution of protein transduction in mice

Shi-Rong Cai, Guang Xu, Michelle Becker-Hapak, Margaret Ma, Steven F. Dowdy, Howard L. McLeod

Journal:

European Journal of Pharmaceutical Sciences

Year:

2006

Language:

english

File:

PDF, 4.10 MB

english, 2006

32

Cationic TAT peptide transduction domain enters cells by macropinocytosis

Ian M. Kaplan, Jehangir S. Wadia, Steven F. Dowdy

Journal:

Journal of Controlled Release

Year:

2005

Language:

english

File:

PDF, 244 KB

english, 2005

33

Corrigendum to “Cationic TAT peptide transduction domain enters cells by macropinocytosis” [J. Control. Release 102 (2005) 247–253]

Ian M. Kaplan, Jehangir S. Wadia, Steven F. Dowdy

Journal:

Journal of Controlled Release

Year:

2005

Language:

english

File:

PDF, 52 KB

english, 2005

34

Corrigendum to “Cationic TAT peptide transduction domain enters cells by macropinocytosis” [J. Control. Release 102 (2005) 247–253]

Ian M. Kaplan, Jehangir S. Wadia, Steven F. Dowdy

Journal:

Journal of Controlled Release

Year:

2005

Language:

english

File:

PDF, 53 KB

english, 2005

35

Anti-cancer protein transduction strategies: reconstitution of p27 tumor suppressor function

Eric L. Snyder, Bryan R. Meade, Steven F. Dowdy

Journal:

Journal of Controlled Release

Year:

2003

Language:

english

File:

PDF, 319 KB

english, 2003

36

Protein transduction: unrestricted delivery into all cells?

Steven R. Schwarze, Keith A. Hruska, Steven F. Dowdy

Journal:

Trends in Cell Biology

Year:

2000

Language:

english

File:

PDF, 1.09 MB

english, 2000

37

Rho Family GTPases Regulate VEGF-Stimulated Endothelial Cell Motility

Norihito Soga, Noriyuki Namba, Sandy McAllister, Lynn Cornelius, Steven L. Teitelbaum, Steven F. Dowdy, Juichi Kawamura, Keith A. Hruska

Journal:

Experimental Cell Research

Year:

2001

Language:

english

File:

PDF, 894 KB

english, 2001

38

TAT-Mediated Protein Transduction into Mammalian Cells

Michelle Becker-Hapak, Sandra S. McAllister, Steven F. Dowdy

Journal:

Year:

2001

Language:

english

File:

PDF, 104 KB

english, 2001

39

The Anonymous American Idol Manuscript Reviewer

Steven F. Dowdy

Journal:

Year:

2006

Language:

english

File:

PDF, 82 KB

english, 2006

40

CDK Inhibitors: Cell Cycle Regulators and Beyond

Arnaud Besson, Steven F. Dowdy, James M. Roberts

Journal:

Developmental Cell

Year:

2008

Language:

english

File:

PDF, 542 KB

english, 2008

41

TAT transduction: the molecular mechanism and therapeutic prospects

Jacob M. Gump, Steven F. Dowdy

Journal:

Trends in Molecular Medicine

Year:

2007

Language:

english

File:

PDF, 167 KB

english, 2007

42

siRNA delivery using peptide transduction domains

Akiko Eguchi, Steven F. Dowdy

Journal:

Trends in Pharmacological Sciences

Year:

2009

Language:

english

File:

PDF, 234 KB

english, 2009

43

Mammary Epithelial Cell-Cycle Progression via the α2β1 Integrin: Unique and Synergistic Roles of the α2 Cytoplasmic Domain

Paul A. Klekotka, Samuel A. Santoro, Alan Ho, Steven F. Dowdy, Mary M. Zutter

Journal:

The American Journal of Pathology

Year:

2001

Language:

english

File:

PDF, 636 KB

english, 2001

44

Reliability and Validity of a Macronutrient Self-Selection Paradigm and a Food Preference Questionnaire

Paula J Geiselman, Ashley M Anderson, Marcia L Dowdy, David B West, Stephen M Redmann, Steven R Smith

Journal:

Physiology & Behavior

Year:

1998

Language:

english

File:

PDF, 162 KB

english, 1998

45

Protein transduction technology offers novel therapeutic approach for brain ischemia

Catherine Denicourt, Steven F. Dowdy

Journal:

Trends in Pharmacological Sciences

Year:

2003

Language:

english

File:

PDF, 226 KB

english, 2003

46

In vivo protein transduction: intracellular delivery of biologically active proteins, compounds and DNA

Steven R Schwarze, Steven F Dowdy

Journal:

Trends in Pharmacological Sciences

Year:

2000

Language:

english

File:

PDF, 76 KB

english, 2000

47

Regulation of G1 cell-cycle progression by oncogenes and tumor suppressor genes

Alan Ho, Steven F Dowdy

Journal:

Current Opinion in Genetics & Development

Year:

2002

Language:

english

File:

PDF, 197 KB

english, 2002

48

TCR Antigen–Induced Cell Death Occurs from a Late G1 Phase Cell Cycle Check Point

Natalie A Lissy, Linda F Van Dyk, Michelle Becker-Hapak, Adita Vocero-Akbani, Jason H Mendler, Steven F Dowdy

Journal:

Year:

1998

Language:

english

File:

PDF, 311 KB

english, 1998

49

p73

Penny K. Davis, Steven F. Dowdy

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2001

Language:

english

File:

PDF, 208 KB

english, 2001

50

Decreased reactivity of allosera against target lymphocytes obtained following thermal injury or long-term cyclosporine treatment

Charles W. Hewitt, Kirby S. Black, Gustavo A. Gonzalez, Steven F. Dowdy, Bruce M. Achauer, Edwin B. Howard

Journal:

Clinical Immunology and Immunopathology

Year:

1987

Language:

english

File:

PDF, 720 KB

english, 1987

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